Reduction of azides to amines mediated by tin bis(1,2-benzenedithiolate)

I Bosch I; AM Costa; M Martin; F Urpi; J Vilarrasa

doi:10.1021/ol991359z

Reduction of azides to amines mediated by tin bis(1,2-benzenedithiolate)

Org Lett. 2000 Feb 10;2(3):397-9. doi: 10.1021/ol991359z.

Authors

I Bosch I¹, AM Costa, M Martin, F Urpi, J Vilarrasa

Affiliation

¹ Departament de Quimica Organica, Facultat de Quimica, Universitat de Barcelona, Catalonia, Spain.

PMID: 10814332
DOI: 10.1021/ol991359z

Abstract

[reaction: see text] A procedure for the conversion of azides to amines, which uses NaBH4 and catalytic amounts of tin(IV) 1,2-benzenedithiolate, is disclosed. Primary, secondary, tertiary, aromatic, and heteroaromatic azides are reduced in excellent yields under very mild conditions.