Bis

K Itami; T Nokami; J Yoshida

doi:10.1021/ol005735n

Bis

Org Lett. 2000 May 4;2(9):1299-302. doi: 10.1021/ol005735n.

Authors

K Itami¹, T Nokami, J Yoshida

Affiliation

¹ Department of Synthetic Chemistry & Biological Chemistry, Kyoto University, Japan.

PMID: 10810732
DOI: 10.1021/ol005735n

Abstract

[formula: see text] The generation of (2-PyMe2Si)2CHLi was easily accomplished by the deprotonation of (2-PyMe2Si)2CH2 using n-BuLi in Et2O. Thus generated (2-PyMe2Si)2CHLi was found to react with a variety of aldehydes and ketones to give the corresponding vinylsilanes in extremely high yields with complete stereoselectivities.