Shotgun sample sequence comparisons between mouse and human genomes

J B Bouck; M L Metzker; R A Gibbs

doi:10.1038/75563

Shotgun sample sequence comparisons between mouse and human genomes

Nat Genet. 2000 May;25(1):31-3. doi: 10.1038/75563.

Authors

J B Bouck¹, M L Metzker, R A Gibbs

Affiliation

¹ Department of Molecular and Human Genetics, Human Genome Sequencing Center, Baylor College of Medicine, Houston, Texas 77030, USA. jbouck@bcm.tmc.edu

PMID: 10802652
DOI: 10.1038/75563

Abstract

A mixed 'clone-by-clone' and 'whole-genome shotgun' strategy will be used to determine the genomic sequence of the mouse. This method will allow a phase of rapid annotation of the contemporaneous human sequence draft, through whole-genome 'sample sequence comparisons'.

Publication types

Comparative Study
Research Support, U.S. Gov't, P.H.S.

MeSH terms

Animals
Cloning, Molecular
Computational Biology / methods
Female
Genome*
Genomic Library
Humans
Mice
Mice, Inbred C57BL
Rats
Sequence Analysis, DNA / methods
Sequence Homology, Nucleic Acid*

Grants and funding

HG02139/HG/NHGRI NIH HHS/United States