Abstract
Chemokine-chemokine receptor interactions mediate constitutive leukocyte trafficking and leukocyte recruitment to sites of infection and inflammation. We suggest that a multiplicity of leukocyte chemoattractants exists to increase the selectivity of leukocyte recruitment in a range of physiological and pathological settings.
Publication types
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Acute Disease
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Arteriosclerosis / immunology
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Cell Movement
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Chemokines / metabolism*
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Communicable Diseases / immunology
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Humans
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Hypersensitivity / immunology
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Inflammation / immunology
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Leukocytes / immunology
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Leukocytes / metabolism*
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Macrophages / immunology
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Macrophages / metabolism*
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Receptors, Chemokine / metabolism*
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Signal Transduction / immunology
Substances
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Chemokines
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Receptors, Chemokine