Anthoptilides A-E, new Briarane diterpenes from the Australian sea pen Anthoptilum cf. kukenthali

N B Pham; M S Butler; P C Healy; R J Quinn

doi:10.1021/np9903806

Anthoptilides A-E, new Briarane diterpenes from the Australian sea pen Anthoptilum cf. kukenthali

J Nat Prod. 2000 Mar;63(3):318-21. doi: 10.1021/np9903806.

Authors

N B Pham¹, M S Butler, P C Healy, R J Quinn

Affiliation

¹ Queensland Pharmaceutical Research Institute and School of Science, Griffith University, Brisbane, Australia 4111.

PMID: 10757710
DOI: 10.1021/np9903806

Abstract

The Australian sea pen Anthoptilum cf. kukenthali has afforded five new briarane-type diterpenes, anthoptilides A-E. Their structures were determined on the basis of their spectroscopic data. Single-crystal X-ray determination was performed on anthoptilide A. Anthoptilides B and C inhibited the binding of [(3)H]1, 3-dipropyl-8-cyclopentylxanthine ([(3)H]DPCPX) on adenosine A(1) receptors.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Cnidaria / chemistry*
Diterpenes / chemistry
Diterpenes / isolation & purification*
Molecular Structure
Spectrum Analysis

Substances

Diterpenes