Laboratory assessment of the hypertensive individual. Value of the main guidelines for high blood pressure

Arq Bras Cardiol. 1999 Aug;73(2):201-10. doi: 10.1590/s0066-782x1999000800008.
[Article in English, Portuguese]

Abstract

Objective: To determine if abnormal laboratory findings are more common in individuals with hypertension and in those with other risk factors, such as obesity, smoking and alcohol ingestion.

Methods: A study was carried out in the general outpatient clinics of a university hospital (145 individuals without previous diagnosis of hypertension) and the following variables were assessed: high blood pressure (as defined by the VI Joint National Committee on Prevention, Detection and Treatment of High Blood Pressure--VI JNC), obesity [calculated using body mass index (BMI)], tobacco use, and alcoholic ingestion. The laboratory examinations consisted of the following tests: hemogram, glycemia, uric acid, potassium, total/HDL-fraction cholesterol, triglycerides, calcium and creatinine.

Results: High blood pressure was not associated with a higher number of abnormal laboratory tests. Hypertensive individuals with a BMI > or = 25 kg/m2 or normotensive obese individuals, however, had a higher frequency of diabetes (12X), hypertriglyceridemia (3X), and hypercholesterolemia (2X), as compared with hypertensive individuals with BMI < 25 kg/m2 and preobese/normal weight normotensive individuals.

Conclusion: High blood pressure is not associated with a higher frequency of abnormal laboratory tests. The association of high blood pressure and obesity, however, increases the detection of diabetes and dyslipidemias.

MeSH terms

  • Alcoholism / complications
  • Body Mass Index
  • Costs and Cost Analysis
  • Female
  • Humans
  • Hypertension / blood*
  • Hypertension / complications
  • Male
  • Middle Aged
  • Obesity / complications
  • Risk Factors
  • Smoking / adverse effects