A malignant triton tumor with an unbalanced translocation (1;13)(q10;q10) and an isochromosome (8)(q10) as the sole karyotypic abnormalities

Y Hennig; S Löschke; D Katenkamp; S Bartnitzke; J Bullerdiek

doi:10.1016/s0165-4608(99)00183-1

A malignant triton tumor with an unbalanced translocation (1;13)(q10;q10) and an isochromosome (8)(q10) as the sole karyotypic abnormalities

Cancer Genet Cytogenet. 2000 Apr 1;118(1):80-2. doi: 10.1016/s0165-4608(99)00183-1.

Authors

Y Hennig¹, S Löschke, D Katenkamp, S Bartnitzke, J Bullerdiek

Affiliation

¹ Center of Human Genetics and Genetic Counselling, University of Bremen, Bremen, Germany.

PMID: 10731598
DOI: 10.1016/s0165-4608(99)00183-1

Abstract

The karyotype of a malignant nerve sheath tumor with rhabdomyosarcomatous differentiation (malignant triton tumor) of a 58-year-old woman is reported. The tumor revealed an isochromosome for the long arm of chromosome 8 and an unbalanced translocation (1;13)(q10;q10) leading to a gain of the long arm of chromosome 1 as the sole karyotypic abnormalities.

Publication types

Case Reports

MeSH terms

Chromosomes, Human, Pair 1 / genetics
Chromosomes, Human, Pair 13 / genetics
Chromosomes, Human, Pair 8 / genetics
Female
Humans
Isochromosomes / genetics*
Karyotyping
Middle Aged
Neoplasm Recurrence, Local
Neurilemmoma / genetics*
Neurilemmoma / pathology
Rhabdomyosarcoma / genetics*
Rhabdomyosarcoma / pathology
Translocation, Genetic / genetics*
Tumor Cells, Cultured
Uterine Neoplasms / genetics*
Uterine Neoplasms / pathology