A case of chronic lymphocytic leukemia with a constitutional pericentric inversion of chromosome 1

S Palanduz; K Cefle; M Aktan; G Tutkan; S Oztürk; Y Pekçelen

doi:10.1016/s0165-4608(99)00109-0

A case of chronic lymphocytic leukemia with a constitutional pericentric inversion of chromosome 1

Cancer Genet Cytogenet. 2000 Apr 1;118(1):62-4. doi: 10.1016/s0165-4608(99)00109-0.

Authors

S Palanduz¹, K Cefle, M Aktan, G Tutkan, S Oztürk, Y Pekçelen

Affiliation

¹ Division of Medical Genetics, Istanbul University, Istanbul Faculty of Medicine, Istanbul, Turkey.

PMID: 10731593
DOI: 10.1016/s0165-4608(99)00109-0

Abstract

Chronic lymphocytic leukemia (CLL) has been reported to be associated with various chromosomal aberrations, the most common being trisomy 12 and structural rearrangements involving 13q, 11q, and 17p. We present a case of CLL with a constitutional pericentric inversion of chromosome 1.

Publication types

Case Reports
Research Support, Non-U.S. Gov't

MeSH terms

Centromere / genetics*
Chromosome Banding
Chromosome Inversion*
Chromosomes, Human, Pair 1 / genetics*
Humans
Karyotyping
Leukemia, Lymphocytic, Chronic, B-Cell / genetics*
Leukemia, Lymphocytic, Chronic, B-Cell / pathology
Lymphocytes / metabolism
Lymphocytes / pathology
Male
Middle Aged