Gene therapy of malignant gliomas: a phase I study of IL-4-HSV-TK gene-modified autologous tumor to elicit an immune response

Hum Gene Ther. 2000 Mar 1;11(4):637-53. doi: 10.1089/10430340050015824.
No abstract available

Publication types

  • Clinical Trial
  • Clinical Trial, Phase I

MeSH terms

  • Brain Neoplasms / genetics*
  • Brain Neoplasms / immunology
  • Clinical Protocols
  • Genetic Therapy*
  • Glioma / immunology
  • Glioma / therapy*
  • Humans
  • Interleukin-4 / genetics*
  • Simplexvirus / enzymology
  • Simplexvirus / genetics*
  • Thymidine Kinase / genetics*
  • Transduction, Genetic

Substances

  • Interleukin-4
  • Thymidine Kinase