Abstract
Urine was concentrated 20-fold for assay for CAg of Schistosoma japonicum. mAb-RIHA and mAb-DotELISA were positive in 78, 31% and 65.06% of cases respectively, of 83 patients with acute schistosomiasis. The false positive rates in 101 healthy controls were 14.85% and 0%, respectively. Cross-reactions (using mAb-RIHA) were seen in 16.36% and 14.28% of patients with clonorchiasis, 49 patients with ankylostomiasis, respectively. Corresponding figures for mAb-DotELISA were 0% and 0%.
MeSH terms
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Acute Disease
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Antibodies, Monoclonal*
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Antigens, Helminth*
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Case-Control Studies
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Clonorchiasis / immunology
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Clonorchiasis / urine
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Cross Reactions
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Enzyme-Linked Immunosorbent Assay / methods*
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False Positive Reactions
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Glycoproteins / immunology*
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Glycoproteins / urine*
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Helminth Proteins / immunology*
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Helminth Proteins / urine*
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Hookworm Infections / immunology
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Hookworm Infections / urine
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Humans
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Reproducibility of Results
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Schistosomiasis japonica / drug therapy
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Schistosomiasis japonica / immunology*
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Schistosomiasis japonica / urine*
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Sensitivity and Specificity
Substances
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Antibodies, Monoclonal
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Antigens, Helminth
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Glycoproteins
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Helminth Proteins
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circulating anodic antigen, Schistosoma mansoni