Abstract
Two oleanane-type oligoglycosides, cernuosides A (1) and B (2), were isolated from the roots of Pulsatilla cernua (Ranunculaceae). Structure elucidation was accomplished by 1D and 2D NMR (DQF-COSY, TOCSY, HMQC, HMBC, and ROESY) methods, FABMS, and hydrolysis. Both compounds showed moderate activity against sucrase.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Carbohydrate Sequence
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China
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Enzyme Inhibitors / isolation & purification*
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Enzyme Inhibitors / pharmacology
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Glycosides / isolation & purification*
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Glycosides / pharmacology
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Hydrolysis
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Intestine, Small / drug effects
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Intestine, Small / enzymology
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Magnetic Resonance Spectroscopy
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Molecular Sequence Data
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Oleanolic Acid* / analogs & derivatives*
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Plant Roots / chemistry
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Plants, Medicinal / chemistry*
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Rats
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Spectrometry, Mass, Fast Atom Bombardment
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Sucrase / antagonists & inhibitors*
Substances
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Enzyme Inhibitors
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Glycosides
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cernuoside A
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cernuoside B
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Oleanolic Acid
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Sucrase