Synthesis of selected aminodeoxy analogues of galabiose and globotriose

H C Hansen; G Magnusson

doi:10.1016/s0008-6215(99)00229-3

Synthesis of selected aminodeoxy analogues of galabiose and globotriose

Carbohydr Res. 1999 Dec 12;322(3-4):166-80. doi: 10.1016/s0008-6215(99)00229-3.

Authors

H C Hansen¹, G Magnusson

Affiliation

¹ Center for Chemistry and Chemical Engineering, Lund University, Sweden.

PMID: 10637981
DOI: 10.1016/s0008-6215(99)00229-3

Abstract

Six aminodeoxy 2-(trimethylsilyl)ethyl (Me3SiEt) glycoside analogues of galabiose (4'- and 6'-aminodeoxy) and globotriose (6"-, 4"-, 2"-, and 6'-aminodeoxy) were synthesized by glycosylation of protected Me3SiEt galactoside and lactoside acceptors with azido-substituted monosaccharide donors, followed by reduction of the azido groups and removal of the protecting groups.

Publication types

Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, P.H.S.

MeSH terms

Disaccharides / chemistry*
Glycosylation
Magnetic Resonance Spectroscopy
Models, Chemical
Trisaccharides / chemistry*

Substances

Disaccharides
Trisaccharides
4-O-alpha-D-galactopyranosyl-D-galactose
globotriose