Intranuclear inclusions and the ubiquitin-proteasome pathway: digestion of a red herring?

Neuron. 1999 Dec;24(4):765-6. doi: 10.1016/s0896-6273(00)81022-3.
No abstract available

MeSH terms

  • Adenosine Triphosphatases / metabolism*
  • Animals
  • Ataxin-1
  • Ataxins
  • Cysteine Endopeptidases / metabolism*
  • Humans
  • Inclusion Bodies / physiology*
  • Ligases / genetics
  • Mice
  • Multienzyme Complexes / metabolism*
  • Nerve Tissue Proteins / genetics
  • Neurons / metabolism
  • Neurons / ultrastructure*
  • Nuclear Proteins / genetics
  • Peptides / metabolism
  • Proteasome Endopeptidase Complex
  • Protein Folding
  • Ubiquitin-Protein Ligases
  • Ubiquitins / metabolism*

Substances

  • ATXN1 protein, human
  • Ataxin-1
  • Ataxins
  • Atxn1 protein, mouse
  • Multienzyme Complexes
  • Nerve Tissue Proteins
  • Nuclear Proteins
  • Peptides
  • Ubiquitins
  • polyglutamine
  • Ubiquitin-Protein Ligases
  • Cysteine Endopeptidases
  • Proteasome Endopeptidase Complex
  • Adenosine Triphosphatases
  • Ligases