Concordance of primary generalised epilepsy and carbamazepine hypersensitivity in monozygotic twins

S G Edwards; V Hubbard; S Aylett; D Wren

doi:10.1136/pgmj.75.889.680

Concordance of primary generalised epilepsy and carbamazepine hypersensitivity in monozygotic twins

Postgrad Med J. 1999 Nov;75(889):680-1. doi: 10.1136/pgmj.75.889.680.

Authors

S G Edwards¹, V Hubbard, S Aylett, D Wren

Affiliation

¹ Department of Clinical Neurology, St Mary's Hospital, Paddington, London, UK.

Abstract

In this paper we describe the previously unreported phenomenon of a carbamazepine-induced mucocutaneous syndrome in identical twins. These twins had developed primary generalised epilepsy within 2 months of each other.

Publication types

Case Reports

MeSH terms

Adolescent
Anticonvulsants / adverse effects*
Anticonvulsants / therapeutic use
Carbamazepine / adverse effects*
Carbamazepine / therapeutic use
Diseases in Twins*
Drug Eruptions / genetics*
Drug Eruptions / pathology
Electroencephalography
Epilepsy, Generalized / drug therapy
Epilepsy, Generalized / genetics*
Epilepsy, Generalized / pathology
Humans
Male
Twins, Monozygotic

Substances

Anticonvulsants
Carbamazepine