How many mutations does it take to make a tumor?

Proc Natl Acad Sci U S A. 1999 Dec 21;96(26):14675-7. doi: 10.1073/pnas.96.26.14675.
No abstract available

Publication types

  • Comment
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adenomatous Polyps / etiology
  • Adenomatous Polyps / genetics*
  • Cell Transformation, Neoplastic / genetics*
  • Colorectal Neoplasms / etiology
  • Colorectal Neoplasms / genetics*
  • Humans
  • Loss of Heterozygosity
  • Models, Genetic
  • Mutation*