Abstract
Testing of susceptibility to 13 antibiotics was performed with 90 isolates of Lactobacillus, Leuconostoc, and Pediococcus. MICs at which 90% of the isolates tested were inhibited by HMR3647, erythromycin, and ciprofloxacin were 0.015, 0.125 and 32 microg/ml, respectively. The penicillin MIC was > or = 16 microg/ml against 26.2% of the studied Lactobacillus sp. isolates and 50% of Lactobacillus plantarum. HMR3647 showed excellent activity against these genera.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Anti-Bacterial Agents / pharmacology*
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Anti-Infective Agents / pharmacology
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Ciprofloxacin / pharmacology
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Erythromycin / pharmacology
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Ketolides*
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Lactobacillus / drug effects*
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Lactobacillus / genetics
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Leuconostoc / drug effects*
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Leuconostoc / genetics
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Macrolides*
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Microbial Sensitivity Tests
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Pediococcus / drug effects*
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Pediococcus / genetics
Substances
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Anti-Bacterial Agents
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Anti-Infective Agents
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Ketolides
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Macrolides
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Ciprofloxacin
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Erythromycin
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telithromycin