Abstract
Eight new labdane-type diterpenes (1-8) were isolated from the fruit of Vitex rotundifolia along with two known abietane-type diterpenoids (9, 10), and their structures were characterized on the basis of spectroscopic data and X-ray crystallographic analysis. Among them, the abietane-type diterpenoid ferruginol (9) exhibited a stronger antioxidative activity than the standard antioxidant, 3-tert-butyl-4-hydroxyanisole (BHA), using a ferric thiocyanate method.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Antioxidants / chemistry*
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Antioxidants / pharmacology
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Asia
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Bepridil / analogs & derivatives
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Bepridil / chemistry
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Biphenyl Compounds
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Carbohydrate Sequence
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Crystallography, X-Ray
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Diterpenes / chemistry*
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Diterpenes / pharmacology
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Free Radical Scavengers / chemistry
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Free Radical Scavengers / pharmacology
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Free Radicals
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Fruit / chemistry*
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Magnetic Resonance Spectroscopy
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Molecular Conformation
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Molecular Sequence Data
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Picrates*
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Plants, Medicinal / chemistry*
Substances
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Antioxidants
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Biphenyl Compounds
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Diterpenes
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Free Radical Scavengers
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Free Radicals
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Picrates
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Bepridil
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1,1-diphenyl-2-picrylhydrazyl