Expression patterns of zebrafish sox11A, sox11B and sox21

Mech Dev. 1999 Dec;89(1-2):167-71. doi: 10.1016/s0925-4773(99)00199-9.

Abstract

We have cloned three sox genes in zebrafish (Danio rerio), one related to human and chicken SOX21, and two related to mammalian and chicken Sox-11. Zebrafish sox21, sox11A and sox11B transcripts are accumulated in the egg, are present in all cells until gastrulation and become restricted later to the developing central nervous system (CNS); expression in adults is undetectable. sox21 is expressed in the forebrain, midbrain and hindbrain, but maximally at the midbrain-hindbrain junction; sox11A,B have a widespread and dynamic expression in the CNS, but in contrast to sox21 are absent at the midbrain-hindbrain boundary.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Blastocyst
  • Brain / embryology
  • Cloning, Molecular
  • Embryo, Nonmammalian
  • Gene Expression Regulation, Developmental*
  • High Mobility Group Proteins / genetics*
  • High Mobility Group Proteins / metabolism
  • Molecular Sequence Data
  • Neoplasm Proteins / genetics*
  • Neoplasm Proteins / metabolism
  • SOX Transcription Factors
  • SOXC Transcription Factors
  • Sequence Homology, Amino Acid
  • Transcription, Genetic
  • Zebrafish / embryology*
  • Zebrafish / genetics*
  • Zebrafish Proteins*

Substances

  • High Mobility Group Proteins
  • Neoplasm Proteins
  • SOX Transcription Factors
  • SOXC Transcription Factors
  • Sox11 protein, mouse
  • Zebrafish Proteins
  • sox11a protein, zebrafish
  • sox11b protein, zebrafish

Associated data

  • GENBANK/U85090
  • GENBANK/U85091
  • GENBANK/U85092