Renal cell carcinoma with massive osseous metaplasia and bone marrow elements

R K Cribbs; M Ishaq; M Arnold; J O'Brien; J Lamb; W L Frankel

doi:10.1016/s1092-9134(99)80025-2

Renal cell carcinoma with massive osseous metaplasia and bone marrow elements

Ann Diagn Pathol. 1999 Oct;3(5):294-9. doi: 10.1016/s1092-9134(99)80025-2.

Authors

R K Cribbs¹, M Ishaq, M Arnold, J O'Brien, J Lamb, W L Frankel

Affiliation

¹ Departments of Pathology, Surgery, and Medicine, The Ohio State University Medical Center, Columbus, OH 43210, USA.

PMID: 10556476
DOI: 10.1016/s1092-9134(99)80025-2

Abstract

Focal calcifications are frequently seen in renal masses and may be present in renal cell carcinomas. Metaplastic bone formation, on the other hand, is a rare event. We report a unique case of a large calcified renal cell carcinoma with massive osseous metaplasia and bone marrow elements. The clinical and pathologic differential diagnosis for this tumor is discussed along with a review of the literature on this unusual phenomenon.

Publication types

Case Reports

MeSH terms

Biomarkers, Tumor / analysis
Bone Marrow / pathology*
Calcinosis / diagnostic imaging
Calcinosis / pathology
Carcinoma, Renal Cell / chemistry
Carcinoma, Renal Cell / diagnostic imaging
Carcinoma, Renal Cell / pathology*
Female
Humans
Immunoenzyme Techniques
Kidney Neoplasms / chemistry
Kidney Neoplasms / diagnostic imaging
Kidney Neoplasms / pathology*
Metaplasia
Middle Aged
Ossification, Heterotopic / diagnostic imaging
Ossification, Heterotopic / metabolism
Ossification, Heterotopic / pathology*
Tomography, X-Ray Computed

Substances

Biomarkers, Tumor