Thirty six cases of molar pregnancy treated by Manual Vacuum Aspiration (MVA) were reviewed in the Instituto Nacional de Perinatología from January 1st to october 31, 1997. Molar pregnancy rate was 2.3 per 1000 pregnancies. Sixty percent of the cases occurred in women aged 20-30 years old. Previous molar pregnancy was the most frequent risk factor found, it was present in 44.5% of the cases. The mean gestational age was 12.6 weeks. Peridural blocking was used for anesthesia de 86.1% of the cases, in the remainder general anesthesia was used. MVA was performed by different surgeons, following the technique that has been previously reported. Twelve women received sharp curettage immediately after MVA. There were tree women with bleeding complications (1000 cc or more), one case needed blood transfusion. In two cases the evacuation was incomplete. Seven cases became persistent trophoblastic disease. The histopathologic report was consistent with complete molar pregnancy la more than 90% of the cases. Oral contraceptives were selected by 66.7% of the women after the evacuation. It was concluded that MVA is a safe and effective method for the evacuation of molar pregnancy.