The role of minimally invasive surgery continues to expand in all the specialties and subspecialties of surgery. At one time, obesity and pregnancy were considered a relative contraindication to laparoscopic surgery. With improved technology and skills, surgeons are able to operate on patients who were once considered to be at too high a risk for laparoscopic surgery. Herein, laparoscopic splenectomy performed at the time of Caesarean section is reported. This case demonstrates the safety and efficacy of laparoscopic splenectomy in a morbidly obese female in the immediate postpartum time.