Development of a predictive statistical model for the analgesic activity of a family of imides

Pharmazie. 1999 Sep;54(9):698-704.

Abstract

Quantitative structure-activity relationship (QSAR) studies were done with a family of cyclic imides. Promising efforts to create a QSAR model with substantial predictive power for the design of novel cyclic imides with improved analgesic activity are reported.

MeSH terms

  • Analgesics / chemistry*
  • Analgesics / pharmacology*
  • Imides / chemistry*
  • Imides / pharmacology*
  • Models, Statistical
  • Models, Theoretical
  • Structure-Activity Relationship

Substances

  • Analgesics
  • Imides