Abstract
Acidocalcisomes are novel acidic Ca2+ storage organelles found in trypanosomatids and apicomplexan parasites, abundant in the intracellular stages of these parasites, and characterized by their high electron density, and high content of phosphorus, Ca2+, Mg2+, Na+ and Zn2+. A number of energy-utilizing pumps and exchangers have been found in these organelles, which underlines their importance in the homeostasis of different elements, as discussed here by Roberto Docampo and Silvia Moreno.
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, P.H.S.
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Review
MeSH terms
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Animals
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Apicomplexa / chemistry
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Apicomplexa / metabolism*
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Apicomplexa / ultrastructure
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Calcium / analysis
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Calcium / metabolism*
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Magnesium / analysis
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Magnesium / metabolism
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Microscopy, Electron
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Microscopy, Fluorescence
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Organelles / chemistry
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Organelles / metabolism*
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Organelles / ultrastructure
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Polyphosphates / chemistry
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Sodium / analysis
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Sodium / metabolism
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Trypanosomatina / chemistry
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Trypanosomatina / metabolism*
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Trypanosomatina / ultrastructure
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Zinc / analysis
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Zinc / metabolism
Substances
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Polyphosphates
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Sodium
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Magnesium
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Zinc
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Calcium