An ethnopharmacological survey for potential angiotensin converting enzyme inhibitors from Indian medicinal plants

B Somanadhan; G Varughese; P Palpu; R Sreedharan; L Gudiksen; U W Smitt; U Nyman

doi:10.1016/s0378-8741(98)00201-3

An ethnopharmacological survey for potential angiotensin converting enzyme inhibitors from Indian medicinal plants

J Ethnopharmacol. 1999 May;65(2):103-12. doi: 10.1016/s0378-8741(98)00201-3.

Authors

B Somanadhan¹, G Varughese, P Palpu, R Sreedharan, L Gudiksen, U W Smitt, U Nyman

Affiliation

¹ Tropical Botanic Garden and Research Institute, Pacha-Palode, Thiruvananthapuram, Kerala, India.

PMID: 10465650
DOI: 10.1016/s0378-8741(98)00201-3

Abstract

Plants used in different traditional systems of Indian medicine and some relatives/substitutes have been investigated for their angiotensin converting enzyme (ACE) inhibitory activity. They were selected on the basis of their usage as cardiotonics, diuretics and other uses related to the symptoms of hypertension. Out of the 73 species investigated, 22 showed more than 50% ACE inhibitory activity.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Angiotensin-Converting Enzyme Inhibitors / isolation & purification
Angiotensin-Converting Enzyme Inhibitors / pharmacology*
Antihypertensive Agents / pharmacology*
Cardiotonic Agents / isolation & purification
Cardiotonic Agents / pharmacology*
Chromatography, High Pressure Liquid
Diuretics / isolation & purification
Diuretics / pharmacology*
India
Medicine, Ayurvedic
Plants, Medicinal / chemistry*

Substances

Angiotensin-Converting Enzyme Inhibitors
Antihypertensive Agents
Cardiotonic Agents
Diuretics