Neurosurgical management of brain abscesses in children

Childs Nerv Syst. 1999 Jul;15(6-7):309-17. doi: 10.1007/s003810050400.

Abstract

The authors review the management of brain abscesses (BAbs) in 59 pediatric cases. The major surgical procedure used to treat them was repeated puncture and aspiration (51 cases, or 86.44%), excision (8 cases - 13.56%) being of secondary importance. The main etiology was metastatic lesions (24 cases - 40.68%), those due to cyanotic congenital heart disease being the most frequent. Single lesions dominated (41 cases - 69.49%). Gram-positive cocci were the main bacteria involved (31 cases, 52.5%). CT scan represented the main tool in the diagnosis and follow-up. Puncture and aspiration in BAbs led to a significant decrease in mortality (7 cases - 11.86%), and the incidence of seizures and neurological deficits was also reduced. Mortality was significantly correlated with the following factors: consciousness status, multiple BAbs location and hematogenous dissemination. There were recurrences in 11 cases (18.64%), all observed after aspiration procedures. The current concepts for complex management of BAbs, as reflected in recent literature data, are reviewed, with particular emphasis on the use of real-time CT or ultrasound-guided operative techniques.

Publication types

  • Review

MeSH terms

  • Brain Abscess / etiology*
  • Brain Abscess / microbiology
  • Brain Abscess / surgery*
  • Child
  • Child, Preschool
  • Female
  • Humans
  • Incidence
  • Male
  • Neurosurgical Procedures / methods
  • Retrospective Studies
  • Risk Factors
  • Survival Analysis
  • Treatment Outcome