A case of neuroleptic-induced unilateral akathisia with periodic limb movements in the opposite side during sleep

Abstract

We report on a patient with schizoaffective disorder who developed unilateral akathisia. This is the first case report of a patient with neuroleptic-induced unilateral akathisia on whom an all-night polysomnogram was recorded. On the polysomnogram we observed right side periodic limb movements (PLM) with left side unilateral akathisia, and after her akathisia disappeared, the PLM also disappeared. Brain MRI findings and neurological findings were within normal limits. The pathogenetic lesion causing akathisia could not be elucidated.