Thirty cases of IgA nephropathy having been diagnosed by biopsy with kidney puncture were selected. The treatment was based on the differentiation of syndromes in traditional Chinese medicine (TCM). The disease was divided into 4 stages: the initial stage with the lesion in the lung and kidney, the stable stage with the lesion in the spleen and kidney, the late stage with the lesion in the liver and kidney, and the recurrent stage. They were treated by TCM. Of them, 10 cases were completely alleviated, 13 markedly alleviated, 4 improved, and 3 ineffective, the total effective rate being 90%.