A case of Down's syndrome associated with progressive extradural neuroblastoma

Pediatr Surg Int. 1999 Jul;15(5-6):373-5. doi: 10.1007/s003830050601.

Abstract

We describe a case of Down's syndrome associated with progressive extradural neuroblastoma. Postmortem aspiration of the bone marrow revealed diffuse infiltration by tumor cells, in which trisomy 21 was found by fluorescence in hybridization in situ.

Publication types

  • Case Reports

MeSH terms

  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Bone Marrow Examination
  • Child
  • Down Syndrome / complications*
  • Down Syndrome / diagnosis
  • Epidural Neoplasms / complications*
  • Epidural Neoplasms / diagnosis*
  • Epidural Neoplasms / therapy
  • Fatal Outcome
  • Humans
  • In Situ Hybridization, Fluorescence
  • Laminectomy
  • Magnetic Resonance Imaging
  • Male
  • Neuroblastoma / complications*
  • Neuroblastoma / diagnosis*
  • Neuroblastoma / therapy
  • Prognosis
  • Radiotherapy, Adjuvant