Abstract
Surgical patients randomly assigned to standard pain control had postoperative subcutaneous oxygen partial pressures that were significantly less than patients given better pain treatment. Our data suggest that control of postoperative pain is a major determinant of surgical-wound infection and should be given the same consideration as maintaining adequate vascular volume and normothermia.
Publication types
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Clinical Trial
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Comparative Study
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Letter
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Randomized Controlled Trial
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Adolescent
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Adult
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Anesthetics, Local / administration & dosage*
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Female
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Humans
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Injections, Intra-Articular
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Ischemia / prevention & control
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Knee / surgery*
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Lidocaine / administration & dosage*
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Male
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Middle Aged
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Oxygen / metabolism*
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Pain Measurement
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Pain, Postoperative / drug therapy*
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Skin / blood supply
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Surgical Wound Infection / prevention & control
Substances
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Anesthetics, Local
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Lidocaine
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Oxygen