Transcription factors: the right combination for the DNA lock

S Khorasanizadeh; F Rastinejad

doi:10.1016/s0960-9822(99)80281-4

Transcription factors: the right combination for the DNA lock

Curr Biol. 1999 Jun 17;9(12):R456-8. doi: 10.1016/s0960-9822(99)80281-4.

Authors

S Khorasanizadeh¹, F Rastinejad

Affiliation

¹ Department of Chemistry, University of Maryland, Baltimore County, Baltimore, Maryland 21250, USA.

PMID: 10375516
DOI: 10.1016/s0960-9822(99)80281-4

Abstract

Recently determined structures of complexes between homeodomain proteins, their cofactors and DNA have provided new insights into the way pairs of transcription factors can collaborate to select the appropriate target DNA-binding sites during development.

Publication types

Review

MeSH terms

Animals
Binding Sites
DNA / chemistry*
DNA / metabolism
Homeodomain Proteins / chemistry
Homeodomain Proteins / metabolism
Macromolecular Substances
Models, Molecular
Nucleic Acid Conformation
Protein Conformation
Transcription Factors / chemistry*
Transcription Factors / metabolism

Substances

Homeodomain Proteins
Macromolecular Substances
Transcription Factors
DNA