Abstract
Purpose:
To report an eye with corneal endotheliitis and increased intraocular pressure in which the trabeculum demonstrated immunoreactivity for herpes simplex virus.
Method:
Case report. A 62-year-old man presented with increased intraocular pressure, keratic precipitates, and corneal stromal edema in his left eye. The tissue excised during trabeculectomy was immunohistochemically examined for herpetic viruses.
Result:
Immunoreactivity for herpes simplex virus was identified in the trabeculum.
Conclusion:
Herpes simplex virus may cause trabeculitis and increased intraocular pressure in patients with corneal endotheliitis.
MeSH terms
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Acyclovir / therapeutic use
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Antibodies, Viral
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Antigens, Viral / analysis
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Antiviral Agents / therapeutic use
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Corneal Edema / pathology
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Corneal Edema / virology
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Endothelium, Corneal / drug effects
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Endothelium, Corneal / pathology
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Endothelium, Corneal / virology*
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Herpesvirus 1, Human / immunology*
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Humans
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Immunoenzyme Techniques
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Intraocular Pressure
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Keratitis, Herpetic / drug therapy
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Keratitis, Herpetic / pathology
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Keratitis, Herpetic / virology*
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Male
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Middle Aged
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Trabecular Meshwork / surgery
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Trabecular Meshwork / virology*
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Trabeculectomy
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Visual Acuity
Substances
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Antibodies, Viral
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Antigens, Viral
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Antiviral Agents
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Acyclovir