Herpes simplex virus in the trabeculum of an eye with corneal endotheliitis

Am J Ophthalmol. 1999 Jun;127(6):721-2. doi: 10.1016/s0002-9394(99)00018-5.

Abstract

Purpose: To report an eye with corneal endotheliitis and increased intraocular pressure in which the trabeculum demonstrated immunoreactivity for herpes simplex virus.

Method: Case report. A 62-year-old man presented with increased intraocular pressure, keratic precipitates, and corneal stromal edema in his left eye. The tissue excised during trabeculectomy was immunohistochemically examined for herpetic viruses.

Result: Immunoreactivity for herpes simplex virus was identified in the trabeculum.

Conclusion: Herpes simplex virus may cause trabeculitis and increased intraocular pressure in patients with corneal endotheliitis.

Publication types

  • Case Reports

MeSH terms

  • Acyclovir / therapeutic use
  • Antibodies, Viral
  • Antigens, Viral / analysis
  • Antiviral Agents / therapeutic use
  • Corneal Edema / pathology
  • Corneal Edema / virology
  • Endothelium, Corneal / drug effects
  • Endothelium, Corneal / pathology
  • Endothelium, Corneal / virology*
  • Herpesvirus 1, Human / immunology*
  • Humans
  • Immunoenzyme Techniques
  • Intraocular Pressure
  • Keratitis, Herpetic / drug therapy
  • Keratitis, Herpetic / pathology
  • Keratitis, Herpetic / virology*
  • Male
  • Middle Aged
  • Trabecular Meshwork / surgery
  • Trabecular Meshwork / virology*
  • Trabeculectomy
  • Visual Acuity

Substances

  • Antibodies, Viral
  • Antigens, Viral
  • Antiviral Agents
  • Acyclovir