A case of SLE with acute, subacute and chronic cutaneous lesions successfully treated with Dapsone

Lupus. 1999;8(3):240-3. doi: 10.1191/096120399678847713.

Abstract

We describe a patient with systemic lupus erythematosus (SLE) who exhibited severe cutaneous involvement characterized by the simultaneous presence of acute, subacute and discoid lesions in association with anti-S1 antibodies. After she failed to respond to chloroquine, medium to low dose steroids, steroid pulses, retinoids and cyclophosphamide, the patient was treated with Dapsone and a dramatic improvement in the cutaneous lesions was seen after only one month.

Publication types

  • Case Reports

MeSH terms

  • Acute Disease
  • Adult
  • Anti-Inflammatory Agents, Non-Steroidal / therapeutic use*
  • Chronic Disease
  • Dapsone / therapeutic use*
  • Female
  • Humans
  • Lupus Erythematosus, Cutaneous / drug therapy*
  • Lupus Erythematosus, Cutaneous / pathology
  • Lupus Erythematosus, Discoid / drug therapy
  • Lupus Erythematosus, Discoid / pathology
  • Lupus Erythematosus, Systemic / drug therapy*
  • Lupus Erythematosus, Systemic / pathology

Substances

  • Anti-Inflammatory Agents, Non-Steroidal
  • Dapsone