Corneal sensitivity after photorefractive keratectomy and laser in situ keratomileusis for low myopia

Am J Ophthalmol. 1999 May;127(5):497-504. doi: 10.1016/s0002-9394(98)00444-9.

Abstract

Purpose: To evaluate and compare the recovery of postoperative corneal sensitivity after laser in situ keratomileusis and photorefractive keratectomy for the correction of low myopia.

Methods: In a prospective study, 17 consecutive eyes (17 patients) underwent laser in situ keratomileusis to correct myopia ranging from -3.25 to -6.75 diopters, and another 18 consecutive eyes (18 patients) underwent photorefractive keratectomy to correct myopia from -3.12 to -7.00 diopters. Corneal sensitivity was tested preoperatively and 1 week and 1, 3, and 6 months postoperatively using the Cochet-Bonnet esthesiometer. Corneal sensitivity was tested at the center of the cornea, and in four additional central points 2 mm from the corneal center (nasal, inferior, temporal, and superior).

Results: Corneal sensitivity after laser in situ keratomileusis was reduced at the ablated zone during the first 3 months after surgery (Wilcoxon rank sum test, P < .05), and only after 6 months it returned to its preoperative values. However, corneal sensitivity recovered its preoperative values 1 month after photorefractive keratectomy (Wilcoxon rank sum test, P > .05), except for the central corneal point, where 3 months were required. Comparing both groups, corneal sensitivity was more depressed after laser in situ keratomileusis than after photorefractive keratectomy during the first 3 months (Mann-Whitney test, P < .05), except for the nasal central point, although no differences were found between both groups at 6 months (P > .05).

Conclusions: In the correction of low myopia, corneal sensitivity at the ablated zone was more depressed after laser in situ keratomileusis than after photorefractive keratectomy during the first 3 months after surgery. Only after 6 months were corneal sensitivity values similar in both groups.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Cornea / innervation
  • Cornea / physiology*
  • Cornea / surgery
  • Corneal Stroma / surgery
  • Diagnostic Techniques, Ophthalmological
  • Female
  • Humans
  • Lasers, Excimer
  • Male
  • Myopia / physiopathology
  • Myopia / surgery*
  • Ophthalmic Nerve / physiology
  • Photorefractive Keratectomy*
  • Prospective Studies
  • Sensation / physiology*
  • Surgical Flaps
  • Time Factors