Insulin increases in vitro production of Th2 profile cytokines in peripheral blood cultures in subjects at high risk of diabetes type 1 and patients with newly diagnosed IDDM

Horm Metab Res. 1999 Apr;31(4):289-92. doi: 10.1055/s-2007-978736.
No abstract available

MeSH terms

  • Adolescent
  • Adult
  • Cells, Cultured
  • Cytokines / biosynthesis*
  • Diabetes Mellitus, Type 1 / blood*
  • Female
  • Humans
  • Insulin / pharmacology*
  • Interferon-gamma / biosynthesis
  • Interleukin-10 / biosynthesis
  • Interleukin-4 / biosynthesis
  • Male
  • Niacinamide / pharmacology
  • Phytohemagglutinins / pharmacology
  • T-Lymphocytes, Helper-Inducer / drug effects*
  • T-Lymphocytes, Helper-Inducer / metabolism*

Substances

  • Cytokines
  • Insulin
  • Phytohemagglutinins
  • Interleukin-10
  • Interleukin-4
  • Niacinamide
  • Interferon-gamma