Interferon alpha treatment of molluscum contagiosum in immunodeficiency

Arch Dis Child. 1999 Jan;80(1):77-9. doi: 10.1136/adc.80.1.77.

Abstract

A sister (aged 6 years) and brother (aged 8 years) presented four months apart with severe molluscum contagiosum. Both children demonstrated clinical and laboratory evidence of combined immunodeficiency. The extent of skin involvement by molluscum contagiosum precluded conventional treatment as well as intralesional interferon alpha (IFN alpha). Both subjects responded well to subcutaneous IFN alpha.

Publication types

  • Case Reports

MeSH terms

  • Antiviral Agents / therapeutic use*
  • Child
  • Female
  • Humans
  • Immunoglobulins, Intravenous
  • Injections, Subcutaneous
  • Interferon-gamma / therapeutic use*
  • Male
  • Molluscum Contagiosum / therapy*
  • Severe Combined Immunodeficiency / complications*
  • Severe Combined Immunodeficiency / therapy

Substances

  • Antiviral Agents
  • Immunoglobulins, Intravenous
  • Interferon-gamma