Synchronous appearance of keratoacanthomas in burn scar and skin graft donor site shortly after injury

J Am Acad Dermatol. 1999 May;40(5 Pt 2):870-1. doi: 10.1053/jd.1999.v40.a94419.

Abstract

Skin malignancies can originate in burn scars (Marjolin's ulcer). The most common is squamous cell carcinoma, usually appearing years after injury. Split-thickness skin graft donor sites as a source of malignant transformation are far less frequent and demonstrate a shorter interval between surgery and tumor onset. Keratoacanthomas have rarely been reported to arise in such scars. We describe the simultaneous occurrence of keratoacanthomas on a spontaneously healed second-degree burn on the flank and in the scar of a skin graft donor site on the thigh, 4 months after a 40% total body surface area burn.

Publication types

  • Case Reports

MeSH terms

  • Burns / complications*
  • Cicatrix / complications*
  • Dermis / pathology
  • Eosinophils / pathology
  • Epidermis / pathology
  • Fibrosis
  • Humans
  • Keratins / analysis
  • Keratoacanthoma / etiology*
  • Keratoacanthoma / pathology
  • Lymphocytes / pathology
  • Male
  • Middle Aged
  • Skin Transplantation / adverse effects*

Substances

  • Keratins