In vitro adhesion and platelet aggregation properties of bacteremia-associated lactobacilli

P V Kirjavainen; E M Tuomola; R G Crittenden; A C Ouwehand; D W Harty; L F Morris; H Rautelin; M J Playne; D C Donohue; S J Salminen

doi:10.1128/IAI.67.5.2653-2655.1999

In vitro adhesion and platelet aggregation properties of bacteremia-associated lactobacilli

Infect Immun. 1999 May;67(5):2653-5. doi: 10.1128/IAI.67.5.2653-2655.1999.

Authors

P V Kirjavainen¹, E M Tuomola, R G Crittenden, A C Ouwehand, D W Harty, L F Morris, H Rautelin, M J Playne, D C Donohue, S J Salminen

Affiliation

¹ Department of Biochemistry and Food Chemistry, University of Turku, Turku, Finland. pirkka.kirjavainen@utu.fi

Abstract

Eight bacteremia-associated Lactobacillus strains were evaluated in vitro for the ability to adhere to human intestinal mucosa and to aggregate platelets. Adherence varied significantly among the strains, and platelet aggregation was induced by three strains. In conclusion, strong binding ability does not appear to be a prerequisite for the involvement of lactobacilli in bacteremia or to their ability to aggregate platelets.

Publication types

Comparative Study
Research Support, Non-U.S. Gov't

MeSH terms

Bacteremia / blood
Bacteremia / etiology*
Bacteremia / microbiology
Bacterial Adhesion / physiology*
Caco-2 Cells
Gram-Positive Bacterial Infections / blood
Gram-Positive Bacterial Infections / etiology*
Gram-Positive Bacterial Infections / microbiology
Humans
In Vitro Techniques
Intestinal Mucosa / microbiology
Lactobacillus / genetics
Lactobacillus / pathogenicity*
Lactobacillus / physiology*
Mucus / microbiology
Platelet Aggregation / physiology*
Species Specificity
Virulence