Phosphor materials used in X-ray image receptors were evaluated by the effective performance index (EPI). EPI describes the dependence of image quality on X-ray to light energy conversion and light diffusion processes. EPI was experimentally determined by means of X-ray luminescence (XLE) and MTF measurements performed on Y2O2S:Eu, Y2O3:Eu, and YVO4:Eu phosphors. The spectral compatibility of these materials with optical detectors (films, photocathodes, photodiodes) was also determined. Highest EPI values were obtained for Y2O2S:Eu-GaAs combination at mammographic energies. All phosphors could be of use in digital X-ray imaging being adequately compatible to silicon photodiodes employed in digital detectors.