Abstract
Recent studies of the semaphorin family of axon guidance signals and their receptors have revealed a surprising versatility in the ways that they can be used solve problems in neural development, and provided new opportunities for understanding how guidance information is interpreted beneath the cell surface.
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, P.H.S.
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Review
MeSH terms
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Animals
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Axons / physiology*
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Cell Adhesion Molecules, Neuronal / chemistry
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Cell Adhesion Molecules, Neuronal / genetics
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Cell Adhesion Molecules, Neuronal / physiology*
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Drosophila Proteins*
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Drosophila melanogaster / embryology
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Drosophila melanogaster / metabolism
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Embryonic and Fetal Development
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Grasshoppers / embryology
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Grasshoppers / metabolism
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Humans
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Insect Proteins / physiology
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Membrane Proteins / physiology
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Mice
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Models, Neurological
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Morphogenesis
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Multigene Family
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Nerve Tissue Proteins / physiology
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Nervous System / cytology
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Nervous System / embryology
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Neuropilin-1
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Receptors, Cell Surface / physiology
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Recombinant Fusion Proteins / physiology
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Semaphorins*
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Signal Transduction
Substances
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Cell Adhesion Molecules, Neuronal
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Drosophila Proteins
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Insect Proteins
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Membrane Proteins
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Nerve Tissue Proteins
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PLXNA1 protein, human
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Plxna1 protein, mouse
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Plxna2 protein, mouse
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Plxna3 protein, mouse
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Plxna4 protein, mouse
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Receptors, Cell Surface
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Recombinant Fusion Proteins
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Sema4d protein, mouse
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Semaphorins
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plexA protein, Drosophila
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Neuropilin-1