Effect of cooled intraocular irrigating solution on the blood-aqueous barrier after cataract surgery

J Cataract Refract Surg. 1999 Apr;25(4):566-8. doi: 10.1016/s0886-3350(99)80057-1.

Abstract

Purpose: To evaluate the effect of cooled intraocular irrigating solution during phacoemulsification on postoperative blood-aqueous barrier (BAB) disturbance.

Setting: Department of Ophthalmology, University of Vienna, Austria.

Methods: In a prospective, randomized clinical study, 40 eyes with senile cataract had phacoemulsification with irrigating solutions cooled to approximately 10 degrees C (n = 20) or at room temperature (n = 20). Surgical procedure and postoperative therapy were otherwise identical in both groups. Postoperative BAB disturbance was assessed with the laser flare-cell meter on days 1, 3, 7, 14, and 28.

Results: Anterior chamber flare was significantly lower in the group with cooled irrigating solution on postoperative day 1. There was no significant between-group difference in flare on any other postoperative day.

Conclusion: Cooled intraocular irrigating solution reduced immediate postoperative inflammation compared with irrigating solution at room temperature. However, this effect was of short duration.

Publication types

  • Clinical Trial
  • Comparative Study
  • Randomized Controlled Trial

MeSH terms

  • Aged
  • Anterior Chamber / pathology
  • Blood-Aqueous Barrier*
  • Cell Count
  • Cold Temperature
  • Cryotherapy*
  • Drug Combinations
  • Epinephrine / administration & dosage
  • Female
  • Follow-Up Studies
  • Gentamicins / administration & dosage
  • Humans
  • Isotonic Solutions / administration & dosage*
  • Laser-Doppler Flowmetry
  • Male
  • Phacoemulsification*
  • Prospective Studies
  • Ringer's Solution
  • Therapeutic Irrigation
  • Uveitis, Anterior / pathology
  • Uveitis, Anterior / prevention & control*

Substances

  • Drug Combinations
  • Gentamicins
  • Isotonic Solutions
  • Ringer's Solution
  • Epinephrine