Yeast cell permeabilizing beta-1,3-glucanases: A tool for the integration of downstream processes and metabolic engineering applications to yeast

P Ferrer; I Diers; J A Asenjo; B A Andrews

Yeast cell permeabilizing beta-1,3-glucanases: A tool for the integration of downstream processes and metabolic engineering applications to yeast

Biotechnol Bioeng. 1998;58(2-3):321-4.

Authors

P Ferrer¹, I Diers, J A Asenjo, B A Andrews

Affiliation

¹ Center for Biochemical Engineering and Biotechnology, Department of Chemical Engineering, Universidad de Chile, Beauchef 861, Santiago, Chile. ferrer@uab-eq.uab.es

PMID: 10191410

Abstract

In this article, we consider the impact on downstream process design resulting from the use of metabolically engineered yeast strains. We address the issue of how manipulation of cell wall permeability can improve the release and subsequent recovery of heterologous products produced in yeast.

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Cell Membrane Permeability
Genetic Engineering / methods*
Glucan 1,3-beta-Glucosidase*
Glycoside Hydrolases / metabolism*
Saccharomyces cerevisiae / enzymology
Saccharomyces cerevisiae / genetics
Yeasts / enzymology*
Yeasts / genetics*

Substances

Glycoside Hydrolases
Glucan 1,3-beta-Glucosidase
beta-1,3-exoglucanase