Mechanisms of optic neuropathy

Curr Opin Ophthalmol. 1997 Dec;8(6):9-15. doi: 10.1097/00055735-199712000-00003.

Abstract

Retinal ganglion cell death is the final common pathway of all human optic neuropathies. An understanding of how these cells die, either at the cell body or after axonal injury, may allow development of strategies for rescuing these cells and therefore ameliorating optic nerve disease.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Animals
  • Axons / pathology
  • Cell Death
  • Humans
  • Ischemia / pathology
  • Optic Nerve / blood supply
  • Optic Nerve / pathology
  • Optic Nerve Diseases / pathology*
  • Retinal Ganglion Cells / pathology