The present study examined the hypothesis that language acculturation of Hispanics in the United States increases their exposure to media-based health information which, in turn, increases medical screening practices and knowledge of cancer symptoms. We interviewed 598 elderly Hispanic women (55-92 years of age) residing in Los Angeles. Language acculturation was measured with items on understanding of English and language preference for interpersonal communication, reading materials, television, and radio. Recency of screening (physician breast exam, Pap smear, routine physical exam, mammogram) and exposure to media-based health information were assessed with Likert-type scales; knowledge of symptoms of breast, cervical, colorectal, and oral cancers was assessed through open-ended questions. The results of multiple regression analyses provide support for the hypothesis. First, language acculturation predicted media exposure after controlling for demographic variables. Second, media exposure predicted screening and symptom knowledge after controlling for language acculturation and the demographic factors. The findings suggest that cancer prevention programs should use Spanish-language media to reach a wider Hispanic audience, especially those who are monolingual.