Nosocomial infections with ceftazidime-resistant Pseudomonas aeruginosa: risk factors and outcome

S C Lee; C P Fung; P Y Liu; T C Wang; L C See; N Lee; S C Chen; W B Shieh

doi:10.1086/501614

Nosocomial infections with ceftazidime-resistant Pseudomonas aeruginosa: risk factors and outcome

Infect Control Hosp Epidemiol. 1999 Mar;20(3):205-7. doi: 10.1086/501614.

Authors

S C Lee¹, C P Fung, P Y Liu, T C Wang, L C See, N Lee, S C Chen, W B Shieh

Affiliation

¹ Division of Infectious Diseases, Chang Gung Memorial Hospital, Keelung, Taiwan, Republic of China.

PMID: 10100550
DOI: 10.1086/501614

Abstract

Prospective studies were conducted for nosocomial Pseudomonas aeruginosa infections from February 1, 1994, to October 30, 1995. Of 97 P. aeruginosa isolates from 97 patients, 35 were resistant to ceftazidime. Logistic regression revealed previous cephalosporin or piperacillin use as independent risk factors for nosocomial ceftazidime-resistant P. aeruginosa infection. Pulsed-field gel electrophoresis revealed that four nosocomial ceftazidime-resistant P. aeruginosa infections were caused by cross-infection, probably through medical personnel.

MeSH terms

Ceftazidime / pharmacology*
Cephalosporins / pharmacology*
Cross Infection / epidemiology
Cross Infection / microbiology
Cross Infection / prevention & control*
Drug Resistance, Microbial
Female
Hospitals, Teaching
Humans
Logistic Models
Male
Middle Aged
Prospective Studies
Pseudomonas Infections / epidemiology
Pseudomonas Infections / microbiology
Pseudomonas Infections / prevention & control*
Pseudomonas aeruginosa / classification
Pseudomonas aeruginosa / drug effects*
Pseudomonas aeruginosa / isolation & purification
Risk Factors
Taiwan

Substances

Cephalosporins
Ceftazidime