Abstract
The results of this randomized, double-blind, placebo-controlled, forced-dose titration study in a diverse population of hypertensive patients in the US indicate that candesartan cilexetil has clinically meaningful dose-related blood pressure-lowering effects and that maximum blood pressure reduction is achieved with doses of 16 and 32 mg given once daily. This study confirms that candesartan cilexetil is a highly effective antihypertensive agent with an excellent tolerability and safety profile, without dose-related adverse effects.
Publication types
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Clinical Trial
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Comparative Study
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Multicenter Study
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Randomized Controlled Trial
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Research Support, Non-U.S. Gov't
MeSH terms
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Antihypertensive Agents / administration & dosage*
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Benzimidazoles / administration & dosage*
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Biphenyl Compounds / administration & dosage*
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Blood Pressure / drug effects
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Dose-Response Relationship, Drug
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Double-Blind Method
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Female
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Humans
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Hypertension / drug therapy*
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Male
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Middle Aged
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Posture
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Prodrugs / administration & dosage
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Tetrazoles*
Substances
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Antihypertensive Agents
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Benzimidazoles
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Biphenyl Compounds
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Prodrugs
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Tetrazoles
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candesartan cilexetil