Abstract
The specific cellular response to muscarinic receptor activation is dependent upon appropriate expression of each of the five muscarinic receptor genes by individual cells. Here we summarise recent work describing some of the genomic regulatory elements and transcriptional mechanisms that control expression of the M1 and M4 genes.
Publication types
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Animals
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DNA-Binding Proteins / metabolism
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Gene Expression Regulation*
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Promoter Regions, Genetic / genetics
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Rats
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Receptor, Muscarinic M1
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Receptor, Muscarinic M4
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Receptors, Muscarinic / genetics*
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Repressor Proteins / metabolism
Substances
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DNA-Binding Proteins
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Receptor, Muscarinic M1
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Receptor, Muscarinic M4
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Receptors, Muscarinic
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Repressor Proteins