Molds on house walls and the effect of their chloroform-extractable metabolites on the respiratory cilia movement of one-day-old chicks in vitro

Folia Microbiol (Praha). 1998;43(6):672-8. doi: 10.1007/BF02816388.

Abstract

The ciliostatic activity of the chloroform-extractable endo- and exometabolites of 5 strains of filamentous fungi--Alternaria sp., Aspergillus glaucus group, Aspergillus versicolor, Cladosporium sphoerospermum, Penicillium sp. and Ulocladium sp.--isolated from molded walls of a dwelling--on tracheal cilia from 1-d-old chicks in vitro was evaluated. Endometabolites of Alternaria sp. and A. versicolor and exometabolites of Ulocladium sp. were the most active, these extracts stopped the ciliary movement within 1 d. The results are discussed in relation to the health status of people living in "moldy" dwellings.

MeSH terms

  • Age Factors
  • Animals
  • Chickens
  • Chloroform
  • Cilia / microbiology*
  • Ciliary Motility Disorders / microbiology*
  • Cladosporium / metabolism
  • Fungal Proteins / isolation & purification
  • Fungal Proteins / metabolism*
  • Household Articles
  • Mycoses / microbiology*
  • Penicillium / metabolism
  • Pneumonia / microbiology*
  • Trachea / microbiology

Substances

  • Fungal Proteins
  • Chloroform