Mapping of the Na+, K(+)-ATPase subunit alpha 2 (ATP1A2) and muscle phosphofructokinase (PFKM) genes in pig by somatic cell hybrid analysis

Anim Genet. 1999 Feb;30(1):57-9. doi: 10.1046/j.1365-2052.1999.00407.x.

Abstract

Two expressed sequence tags were isolated from a porcine skeletal muscle cDNA library and identified as the putative partial cDNAs of the porcine Na+, K(+)-ATPase subunit alpha 2 (ATP1A2) and muscle phosphofructokinase (PFKM) genes after sequencing and homology search. Results of analysis of a pig-rodent somatic cell hybrid panel by PCR allowed the assignments of ATP1A2 to porcine chromosome (chr) 4 and of PFKM to porcine chr 5. These assignments support previously observed conservation of syntenic relationships between human chr 1 and porcine chr 4 and between human chr 12 and porcine chr 5.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Chromosome Mapping / veterinary*
  • Chromosomes, Human, Pair 1
  • Chromosomes, Human, Pair 12
  • Expressed Sequence Tags
  • Humans
  • Muscle, Skeletal / enzymology
  • Phosphofructokinase-1 / genetics*
  • Sequence Homology, Nucleic Acid
  • Sodium-Potassium-Exchanging ATPase / genetics*
  • Swine / genetics*

Substances

  • Phosphofructokinase-1
  • Sodium-Potassium-Exchanging ATPase

Associated data

  • GENBANK/X94254