Primary myeloid leukemia presenting concomitantly with primary multiple myeloma: two cases and an update of the literature

C M Anderson; C E Bueso-Ramos; S A Wallner; M Albitar; T E Rosenzweig; C A Koller

doi:10.3109/10428199909167402

Primary myeloid leukemia presenting concomitantly with primary multiple myeloma: two cases and an update of the literature

Leuk Lymphoma. 1999 Jan;32(3-4):385-90. doi: 10.3109/10428199909167402.

Authors

C M Anderson¹, C E Bueso-Ramos, S A Wallner, M Albitar, T E Rosenzweig, C A Koller

Affiliation

¹ Leukemia Department, The University of Texas M.D. Anderson Cancer Center, Houston 77030, USA.

PMID: 10037039
DOI: 10.3109/10428199909167402

Abstract

We report one case of primary acute myelogenous leukemia (AML) and one case of refractory anemia with excess blasts in transformation (RAEB-T) each presenting concomitantly with multiple myeloma, an unusual finding. The twin diagnoses in each patient were confirmed by cytochemical and immunohistochemical studies, and in one of our cases, by ultrastructural, flow cytometric, and molecular studies. The last three methods have not been previously used to document this phenomenon.

Publication types

Case Reports
Review

MeSH terms

Aged
Anemia, Refractory, with Excess of Blasts / diagnosis
Diagnosis, Differential
Humans
Leukemia, Myeloid / diagnosis*
Leukemia, Myeloid / pathology
Male
Multiple Myeloma / diagnosis*
Multiple Myeloma / pathology