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Global, regional, and national burden of disorders affecting the nervous system, 1990-2021: a systematic analysis for the Global Burden of Disease Study 2021.
GBD 2021 Nervous System Disorders Collaborators. GBD 2021 Nervous System Disorders Collaborators. Lancet Neurol. 2024 Apr;23(4):344-381. doi: 10.1016/S1474-4422(24)00038-3. Epub 2024 Mar 14. Lancet Neurol. 2024. PMID: 38493795 Free PMC article.
We also isolated neurological health loss from conditions for which nervous system morbidity is a consequence, but not the primary feature, including a subset of congenital conditions (ie, chromosomal anomalies and congenital birth defects), neonatal conditions (ie, jaundice, pre …
We also isolated neurological health loss from conditions for which nervous system morbidity is a consequence, but not the primary feature, …
Making sense of flavivirus non-strctural protein 1 in innate immune evasion and inducing tissue-specific damage.
Zeng Q, Liu J, Hao C, Zhang B, Zhang H. Zeng Q, et al. Virus Res. 2023 Oct 15;336:199222. doi: 10.1016/j.virusres.2023.199222. Epub 2023 Sep 16. Virus Res. 2023. PMID: 37716670 Free PMC article. Review.
Flaviviruses include medically important mosquito-borne pathogens, such as Zika virus (ZIKV), Japanese encephalitis virus (JEV), dengue virus (DENV) and West Nile virus (WNV), that cause hundreds of millions of infections each year. ...The flavi …
Flaviviruses include medically important mosquito-borne pathogens, such as Zika virus (ZIKV), Japanese encephalitis virus …
Immunization against Zika by entrapping live virus in a subcutaneous self-adjuvanting hydrogel.
Hao H, Wu S, Lin J, Zheng Z, Zhou Y, Zhang Y, Guo Q, Tian F, Zhao M, Chen Y, Xu X, Hou L, Wang X, Tang R. Hao H, et al. Nat Biomed Eng. 2023 Jul;7(7):928-942. doi: 10.1038/s41551-023-01014-4. Epub 2023 Mar 23. Nat Biomed Eng. 2023. PMID: 36959404
The threat of new viral outbreaks has heightened the need for ready-to-use vaccines that are safe and effective. Here we show that a subcutaneous vaccine consisting of live Zika virus electrostatically entrapped in a self-adjuvanting hydrogel recruited immune cells …
The threat of new viral outbreaks has heightened the need for ready-to-use vaccines that are safe and effective. Here we show that a subcuta …
Virus-CKB 2.0: Viral-Associated Disease-Specific Chemogenomics Knowledgebase.
Hao Y, Chen M, Othman Y, Xie XQ, Feng Z. Hao Y, et al. ACS Omega. 2022 Oct 10;7(42):37476-37484. doi: 10.1021/acsomega.2c04258. eCollection 2022 Oct 25. ACS Omega. 2022. PMID: 36312370 Free PMC article.
To facilitate the research of such treatment, we updated our Virus-CKB 1.0 to Virus-CKB 2.0, which contains 10 kinds of viruses, including enterovirus, dengue virus, hepatitis C virus, Zika virus, herpes simplex virus, Andes orthoh …
To facilitate the research of such treatment, we updated our Virus-CKB 1.0 to Virus-CKB 2.0, which contains 10 kinds of viruse …
Targeted inhibition of Zika virus infection in human cells by CRISPR-Cas13b.
Chen P, Chen M, Chen Y, Jing X, Zhang N, Zhou X, Li X, Long G, Hao P. Chen P, et al. Virus Res. 2022 Apr 15;312:198707. doi: 10.1016/j.virusres.2022.198707. Epub 2022 Feb 9. Virus Res. 2022. PMID: 35150770
Zika virus (ZIKV) outbreaks occurred in recent years on an unprecedented scale, which caused fever and severe complications like Guillain-Barre syndrome in adults and fetal abnormalities. ...Five crRNAs were found to have significant effects (p < 0.001; two-sided …
Zika virus (ZIKV) outbreaks occurred in recent years on an unprecedented scale, which caused fever and severe complications li …
Developing Machine Learning and Statistical Tools to Evaluate the Accessibility of Public Health Advice on Infectious Diseases among Vulnerable People.
Xie W, Ji M, Zhao M, Lam KY, Chow CY, Hao T. Xie W, et al. Comput Intell Neurosci. 2021 Dec 17;2021:1916690. doi: 10.1155/2021/1916690. eCollection 2021. Comput Intell Neurosci. 2021. PMID: 34925484 Free PMC article.
BACKGROUND: From Ebola, Zika, to the latest COVID-19 pandemic, outbreaks of highly infectious diseases continue to reveal severe consequences of social and health inequalities. ...
BACKGROUND: From Ebola, Zika, to the latest COVID-19 pandemic, outbreaks of highly infectious diseases continue to reveal severe cons …
Transcriptome Analysis of Aedes albopictus (Diptera: Culicidae) Larvae Exposed With a Sublethal Dose of Haedoxan A.
Hao H, Zuo Y, Fang J, Sun A, Aioub AAA, Hu Z. Hao H, et al. J Med Entomol. 2021 Nov 9;58(6):2284-2291. doi: 10.1093/jme/tjab089. J Med Entomol. 2021. PMID: 33999150
Aedes albopictus is the vector of arbovirus diseases including yellow fever, dengue, Zika virus, and chikungunya fever, and it poses an enormous threat to human health worldwide. ...
Aedes albopictus is the vector of arbovirus diseases including yellow fever, dengue, Zika virus, and chikungunya fever, and it …
Betulinic acid exhibits antiviral effects against dengue virus infection.
Loe MWC, Hao E, Chen M, Li C, Lee RCH, Zhu IXY, Teo ZY, Chin WX, Hou X, Deng J, Chu JJH. Loe MWC, et al. Antiviral Res. 2020 Dec;184:104954. doi: 10.1016/j.antiviral.2020.104954. Epub 2020 Oct 17. Antiviral Res. 2020. PMID: 33080251
Dengue virus (DENV) is an arthropod-borne virus that has developed into a prominent global health threat in recent decades. ...Betulinic acid also demonstrated antiviral efficacy against other serotypes of DENV, as well as against other mosquito-borne RNA viruses su …
Dengue virus (DENV) is an arthropod-borne virus that has developed into a prominent global health threat in recent decades. .. …
Precise and Programmable Detection of Mutations Using Ultraspecific Riboregulators.
Hong F, Ma D, Wu K, Mina LA, Luiten RC, Liu Y, Yan H, Green AA. Hong F, et al. Cell. 2020 Mar 5;180(5):1018-1032.e16. doi: 10.1016/j.cell.2020.02.011. Epub 2020 Feb 27. Cell. 2020. PMID: 32109416 Free PMC article.
Integrating SNIPRs with portable paper-based cell-free reactions enables convenient isothermal detection of cancer-associated mutations from clinical samples and identification of Zika strains through unambiguous colorimetric reactions....
Integrating SNIPRs with portable paper-based cell-free reactions enables convenient isothermal detection of cancer-associated mutations from …
25 results